Needle-free ballistic powder delivery

By applying Freeze Granulation you will be able to make microparticles with high insulin loading (nanosuspension) suitable for needle-free ballistic drug delivery. The resulting granules are homogeneous and robust with a diameter of around 50-150 µm, with a narrow size distribution and a high content of insulin.

Protein aerosol powders

Freeze granulation, as opposed to spray drying, has been shown to produce protein particles with light and porous characteristics, which offered powders with superior aerosol performance due to favorable aerodynamic properties, suitable granulation technology for protein inhalation powders.

 

Frysgranulering för tillverkning av homogena granuler (in Swedish)

PowderPro har i samarbete med Swerea IVF (då Svenska Keraminstitutet) under 1980-talet vidareutvecklat en alternativ granuleringsteknik – frysgranulering (Freeze Granulation) – vilken möjliggör konservering av homogeniteten från suspension till torrt granulat. Genom att spreja en pulversuspension ner i flytande kväve sker en momentan frysning av dropparna (granulerna). I den efterföljande frystorkningen sublimeras isen utan risk för segregeringseffekter som lätt sker vid konventionell torkning i luft. Resultatet blir sfäriska och friflytande granuler med optimal homogenitet lämpliga för t ex pressning av keramiska komponenter.
Freeze granulation illustration
Freeze granulation illustration
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LED photoluminescence granulation

Freeze Granulation is today used for commercial production of homogeneous granules for the production of oxides used as a ceramic phosphor plate for white illumination in LED Lighting. By using Freeze Granulation of the powder and binder mixture, compared with spray drying, it is possible to manufacture a homogeneous phosphor plate with optimal properties for to generate a soft and warm white light from high power LEDs.

Abrasive granulation

Freeze Granulation is today beeing used for commercial mixing, granulation and drying of different abrasive products. The resulting products have a homogeneous distribution of all active material, like superabrasive particles, resulting in improved milling performance and long tool life.

Please contact us and we will further discuss the opportunities with Freeze Granulation on your powder system and read more on technology and we propose a Granulation Test of your powder system.

LEAN Granulation

Freeze Granulation for LEAN Granulation of your powders and chemicals for optimal homogeneity, improved properties and it saves time and money in lab and production.
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