Nanoembedded Microparticles for Stabilization and Delivery of Drug-Loaded Nanoparticles Bohr A, Water J, Beck-Broichsitter M, Yang M Abstract Nanoparticle-based pharmaceutical products are currently finding their way onto the market as a popular strategy to improve the therapeutic efficacy of numerous drugs, hereunder medications for a targeted treatment of severe diseases (e.g., cancer). Drug-loaded polymer and… Continue reading Nanoembedded Microparticles for Stabilization and Delivery of Drug-Loaded Nanoparticles
Freeze Granulation offers the possibility to produce very soft, spherical granules which show an excellent flowability. The granules can be compressed to compacts of high homogeneity and they are completely redispersable. Freeze Granulation is a granulation technique which combines the advantages of spray drying and freeze drying. Hard granules are prevented by this technique excluding… Continue reading Freeze Granulation of ceramic powders
Freeze granulation, as opposed to spray drying, has been shown to produce protein particles with light and porous characteristics, which offered powders with superior aerosol performance due to favorable aerodynamic properties, suitable granulation technology for protein inhalation powders.
Migration and segregation of the constituents that is common in other granulating processes such as spray drying is avoided in Freeze Granulation. By instant freezing of small droplets critical ice crystal growth is avoided. The freeze drying where the liquid medium is sublimated ensures homogeneity preservation, limited oxidation and soft bonds within the granules. This provides… Continue reading Granule homogeneity
What is the difference between spray drying and Freeze Granulation? For more info, please go to our Pros & Cons. The best way to find out if Freeze Granulation is suitable for your material is to let us do a test granulation. Freeze Granulation will be more expensive than spray drying as it is a… Continue reading Spray drying compared with Freeze Granulation