Spray Freeze Drying of Biologics: A Review and Applications for Inhalation Delivery Susana Farinha, João V Sá, Paulo Roque Lino, Marco Galésio, João Pires, Miguel Ângelo Rodrigues, João Henriques Abstract Biopharmaceuticals have established an indisputable presence in the pharmaceutical pipeline, enabling highly specific new therapies. However, manufacturing, isolating, and delivering these highly complex molecules to… Continue reading Spray Freeze Drying of Biologics: A Review and Applications for Inhalation Delivery
Tag: powders
Granulation of fine eggshell powder to produce feedstock powder for binder jetting additive manufacturing: A feasibility study
Granulation of fine eggshell powder to produce feedstock powder for binder jetting additive manufacturing: A feasibility study Shakil Arman, Fahim Khan, Mostafa Meraj Pasha, Jackson Sanders, Zhijian Pei Abstract This paper explores the feasibility of granulating fine eggshell powder using spray freeze drying to produce feedstock powder for binder jetting additive manufacturing. Fine eggshell powder possesses carbon-capture potential but exhibits poor flowability, causing issues during powder spreading in binder jetting additive… Continue reading Granulation of fine eggshell powder to produce feedstock powder for binder jetting additive manufacturing: A feasibility study
Protein aerosol powders
Protein aerosol powders by Freeze Granulation Freeze granulation, as opposed to spray drying, has been shown to produce protein particles with light and porous characteristics, which offered powders with superior aerosol performance due to favorable aerodynamic properties, suitable granulation technology for protein inhalation powders. Please contact us and we will further discuss the opportunities with Freeze Granulation in your powder system and read… Continue reading Protein aerosol powders
How to make granules from powders
By using Freeze Granulation or Spray Freeze Drying it’s possible to make spherical, homogeneous and dust-free granules with optimal flowability which is critical for automatic uniaxial pressing of for ex ceramics and metal powders.
Wet granulation
Freeze Granulation – homogeneous wet granulation of powders Freeze Granulation is a wet granulation method where the powders, chemicals and binders are first mixed and dispersed in a solvent. In the next step the homogeneous slurry is pumped and sprayed through a nozzle to form droplets, which are sprayed into liquid nitrogen for instant freezing.… Continue reading Wet granulation
Granulation equipment
PowderPro supplies equipment for granulation of various powders and chemicals. Freeze Granulation for improved granule properties compared with spray drying. Granules with no void formation, no migration of fine particles or binders, and no formation of hard dry shell. Spray cooling or rather called spray freezing is the first step in the freeze granulation process where a… Continue reading Granulation equipment
Pressing of powders
Pressing is the dominating shaping technique for ceramics and powder metals. Submicron and/or composite powders require adequate preparation to achieve a pressing performance that ensures dense compaction into a homogeneous state. Conventional powder granulation methods (spray drying, sieve granulation etc) show drawbacks. Migration phenomena cause inhomogeneities and hard granules that do not disintegrate properly during… Continue reading Pressing of powders
Nanoparticles processing
Processing of nanoparticles using Freeze Granulation, Spray Freeze Drying, you will get optimal properties of your nanoparticles when mixing them with other powders or materials. The homogeneity of the powder mixture will be kept throughout the process steps, in spraying, freezing and drying, resulting in a dry granulate with homogeneously distributed nanoparticles.
Plasma spraying
Freeze Granulation is today being used to process plasma spraying powders for to achieve a homogeneous mixture and spherical granules for improved thermal spraying performance. — Please contact us and we will further discuss the opportunities with Freeze Granulation on your powder system and read more on technology and we propose a Granulation Test of… Continue reading Plasma spraying
Homogeneous composite powders
Homogeneous composite powders are beeing made by Freeze Granulation of a homogeneous composite powder slurry.