Inhalable nanocomposite microparticles: Preparation, characterization and factors affecting formulation Elsayed I, AbouGhaly MH Abstract INTRODUCTION: Nanocomposite microparticles are intelligent carriers utilised for pulmonary drug delivery. These carriers are composed of drug-encapsulated nanoparticles dispersed in microstructures of polysaccharides. Upon administration, the inhaled microparticles can penetrate and be deposited deeply in the lung due to their adjusted… Continue reading Inhalable nanocomposite microparticles: Preparation, characterization and factors affecting formulation
Tag: spray freeze drying
Nanoembedded Microparticles for Stabilization and Delivery of Drug-Loaded Nanoparticles
Nanoembedded Microparticles for Stabilization and Delivery of Drug-Loaded Nanoparticles Bohr A, Water J, Beck-Broichsitter M, Yang M Abstract Nanoparticle-based pharmaceutical products are currently finding their way onto the market as a popular strategy to improve the therapeutic efficacy of numerous drugs, hereunder medications for a targeted treatment of severe diseases (e.g., cancer). Drug-loaded polymer and… Continue reading Nanoembedded Microparticles for Stabilization and Delivery of Drug-Loaded Nanoparticles
Pharmaceutical spray freeze drying
Pharmaceutical spray freeze drying Stefan Wanning, Richard Süverkrüp, Alf Lamprecht Abstract Pharmaceutical spray-freeze drying (SFD) includes a heterogeneous set of technologies with primary applications in apparent solubility enhancement, pulmonary drug delivery, intradermal ballistic administration and delivery of vaccines to the nasal mucosa. The methods comprise of three steps: droplet generation, freezing and sublimation drying, which… Continue reading Pharmaceutical spray freeze drying
Nanoparticles processing
Processing of nanoparticles using Freeze Granulation, Spray Freeze Drying, you will get optimal properties of your nanoparticles when mixing them with other powders or materials. The homogeneity of the powder mixture will be kept throughout the process steps, in spraying, freezing and drying, resulting in a dry granulate with homogeneously distributed nanoparticles.
How to avoid doughnut or donut shaped granules?
By using Freeze Granulation – Spray Freeze Drying – you will be able to avoid donut-shaped granules. — Please contact us and we will further discuss the opportunities with Freeze Granulation on your powder system and read more on technology and we propose a Granulation Test of your powder system.
Interested in test-granulation of your material?
If you would like to test-granulate your powders or chemicals using Freeze Granulation, please contact us for details. You send your material and binders to us, we make the test-granulation using freeze granulation and then send the granulated material (granulaes) back to you for your evaluation and testing. Freeze granulation is considered to be a natural tool in most… Continue reading Interested in test-granulation of your material?