Freeze Granulation of Nanomaterials on Slideshare

Please see our presentation Freeze Granulation of Nanomaterials on Slideshare.

How Freeze Granulation can improve the homogeneity of your nanomaterials and make it possible to redisperse a nanomaterial that have been dried.

Please contact us and we will further discuss the opportunities with Freeze Granulation in your powder system and read more on technology and a Granulation Test of your powder system.

Protein aerosol powders

Protein aerosol powders by Freeze Granulation

Freeze granulation, as opposed to spray drying, has been shown to produce protein particles with light and porous characteristics, which offered powders with superior aerosol performance due to favorable aerodynamic properties, suitable granulation technology for protein inhalation powders.

Please contact us and we will further discuss the opportunities with Freeze Granulation in your powder system and read more on technology and we propose a Granulation Test of your powder system.

Protein aerosol powders

Needle-free ballistic powder delivery

Needle-free ballistic powder delivery
Needle-free ballistic powder delivery

Needle-free ballistic powder delivery by applying Freeze Granulation you will be able to make microparticles with high insulin loading (nanosuspension) suitable for needle-free ballistic drug delivery. The resulting granules are homogeneous and robust with a diameter of around 50-150 µm, with a narrow size distribution and a high content of insulin.

Please contact us and we will further discuss the opportunities with Freeze Granulation on your powder system and read more on technology and we propose a Granulation Test of your powder system.

Zeolite granulation

Freeze Granulation of zeolite materials offers the possibility to produce very soft, spherical granules which show an excellent flowability. The granules can be compressed to compacts of high homogeneity and they are completely redispersableFreeze Granulation is a granulation technique which combines the advantages of spray drying and freeze drying. Hard granules and agglomerates are prevented by this technique excluding capillary forces during drying.

Please contact us and we will further discuss the opportunities with Freeze Granulation on your powder system and read more on technology and we propose a Granulation Test of your powder system.

Lab-scale granulator LS-2
Zeolite granulation by LS-2

Spray-freezing and freeze drying

Spray-freezing and freeze drying – Freeze Granulation

PowderPro AB develop, manufacture, market and sell equipment and know-how for Freeze Granulationspray freezing and subsequent freeze drying (lyophilization or cryodesiccation). Freeze Granulation was developed in late 1980s at Swedish Ceramic Institute in Göteborg and it is also a development of Spray Freeze Drying (SFD) and Spray Freezing into Liquid (SFL).

Spray cooling or rather called spray freezing is the first step in the freeze granulation process where a suspension is atomized, sprayed with a nozzle, into a chamber with liquid nitrogen. The small droplets are then rapidly frozen with a minimum of ice crystal growth. The frozen material (granules) are then transferred to a freeze dryer where the ice is removed by sublimation, i e never go through a liquid state that ensure homogeneity preservation.

Below you can see an illustration of the Freeze Granulation process.

Please contact us and we will further discuss the opportunities with Freeze Granulation on your powder system and read more on technology and we propose a Granulation Test of your powder system.

Illustration of Freeze Granulation
Illustration of Freeze Granulation

Nano ice formation in granules

Nano ice in granules by Freeze Granulation

Nano ice formation in granules by Freeze Granulation process is a key factor for the unique homogeneity of particles and binders achieved in the resulting granules. This is especially important for nanopowders, fine particles and binders where migration of these could occur during conventional drying, like spray drying.

Please contact us and we will further discuss the opportunities with Freeze Granulation on your powder system and read more on technology and we propose a Granulation Test of your powder system.

Granule with nano-ice and nanopowder
Nano-ice formation in granules of nanoparticles

LED photoluminescence granulation

LED photoluminescence granulation

Freeze Granulation is today used for commercial production of homogeneous granules for the production of oxides used as a ceramic phosphor plate for white illumination in LED Lighting. By using Freeze Granulation of the powder and binder mixture, compared with spray drying, it is possible to manufacture a homogeneous phosphor plate with optimal properties for to generate a soft and warm white light from high power LEDs.

Please contact us and we will further discuss the opportunities with Freeze Granulation on your powder system and read more on technology and we propose a Granulation Test of your powder system.

LED photoluminescence granulation
LED photoluminescence granulation

Ultrasonic atomisation

Freeze Granulation with ultrasonic atomisation of droplets

Freeze Granulation can be made using ultrasonic atomisation of spherical droplets. The resulting granules have a narrow granule size distribution and the granule size is in general smaller (average 120 micron) compared to a regular spray nozzle. The granulation speed is also slow with about 0.3 to 0.5 litre/h.

Please contact us and we will further discuss the opportunities with Freeze Granulation on your powder system and read more on technology and we propose a Granulation Test of your powder system.

Ultrasonic automisation
Ultrasonic atomisation

Transparent and translucent ceramics

Transparent and translucent ceramics by Freeze Granulation

Freeze Granulation is today being used for commercial manufacturing of transparent and translucent ceramics. The main advantage is to achieve a homogeneous distribution of the starting material which will result in rapid reaction and sintering at low temperature where grain growth of the material will be avoided.

Please contact us and we will further discuss the opportunities with Freeze Granulation on your powder system and read more on technology and we propose a Granulation Test of your powder system.

Transparent and translucent ceramics

POWTECH 2013 – Nürnberg

POWTECH 2013 – Nürnberg. Good and interesting meetings on powder processing and how Freeze Granulation can improve the homogeneity of the granules, for example nanomaterial like CNT – Carbon Nano Tubes.

Please contact us and we will further discuss the opportunities with Freeze Granulation on your powder system and read more on technology and we propose a Granulation Test of your powder system.

POWTECH 2013 - Nürnberg
POWTECH 2013 – Nürnberg

POWTECH 2013 – Nürnberg