Category: Scientific papers

Inhalable clarithromycin liposomal dry powders using ultrasonic spray freeze drying Tiantian Yea, Jiaqi Yub, Qiuhua Luoa, Shujun Wanga, Hak-Kim Chanb Abstract Liposomal dry powder inhalation for the pulmonary administration has a great potential to improve the efficacy of antibiotics while reducing adverse effects. To improve aerosolisation efficiency of liposomal dry powders, we prepared clarithromycin liposomal… Continue reading Inhalable clarithromycin liposomal dry powders using ultrasonic spray freeze drying

Spray freeze-dried nanofibrillated cellulose aerogels with thermal superinsulating properties Clara Jiménez-Saelicesa, Bastien Seantiera, Bernard Cathalab, Yves Grohensa Abstract Nanofibrillated cellulose (NFC) aerogels were prepared by spray freeze-drying (SFD). Their structural, mechanical and thermal insulation properties were compared to those of NFC aerogels prepared by conventional freeze-drying (CFD). The purpose of this investigation is to develop… Continue reading Spray freeze-dried nanofibrillated cellulose aerogels with thermal superinsulating properties

A new class of closed-cell aluminium foams reinforced with carbon nanotubes I. Duartea, E. Venturaa, S. Olherob, J.M.F. Ferreirab Abstract This manuscript reports on the fabrication of closed-cell aluminium alloy foams reinforced with carbon nanotubes (CNTs) through a novel approach that combines the powder metallurgy method with colloidal processing step that grants uniform dispersion of… Continue reading A new class of closed-cell aluminium foams reinforced with carbon nanotubes

Enhancement of oral bioavailability of vitamin E by spray-freeze drying of whey protein microcapsules Parthasarathi S., C. Anandharamakrishnana Abstract Vitamin E microcapsules were effectively prepared using three different techniques: spray drying, freeze-drying and spray freeze-drying with whey protein isolate as an encapsulating agent. The quality of microcapsules was evaluated by particle size distribution, surface morphology,… Continue reading Enhancement of oral bioavailability of vitamin E by spray-freeze drying of whey protein microcapsules

Aerodynamic Droplet Stream Expansion for the Production of Spray Freeze-Dried Powders Wanning S, Süverkrüp R, Lamprecht A Abstract In spray freeze-srying (SFD), a solution is sprayed into a refrigerant medium, frozen, and subsequently sublimation dried, which allows the production of flowable lyophilized powders. SFD allows commonly freeze-dried active pharmaceutical ingredients (e.g., proteins and peptides) to… Continue reading Aerodynamic Droplet Stream Expansion for the Production of Spray Freeze-Dried Powders

Aerosol assisted self-assembly as a route to synthesize solid and hollow spherical lignin colloids and its utilization in layer by layer deposition Mishra PK, Wimmer R Abstract Lignin, a major constituent of plant cell-wall and by-product of paper based industries is traditionally used for low value applications (heat or electricity generation), but its potential in… Continue reading Aerosol assisted self-assembly as a route to synthesize solid and hollow spherical lignin colloids and its utilization in layer by layer deposition

Spray freeze drying as an alternative technique for lyophilization of polymeric and lipid-based nanoparticles Mohamed Ehab Alia, Alf Lamprechta Abstract The use of nanoparticles for drug delivery is still restricted by their limited stability when stored in an aqueous medium. Freeze drying is the standard method for long-term storage of colloidal nanoparticles; however the method… Continue reading Spray freeze drying as an alternative technique for lyophilization of polymeric and lipid-based nanoparticles

Improved transparency and hardness in α-alumina ceramics fabricated by high-pressure SPS of nanopowders Shaghayegh Ghanizadeha, Salvatore Grassob, Prabhu Ramanujamc, Bala Vaidhyanathana, Jon Binnerc, Peter Brownd, Judah Goldwassere Abstract Nanocrystalline alumina powder with an average crystallite size of ≤50 nm has been consolidated by spark plasma sintering (SPS) and hot pressing (HP) with a view to… Continue reading Improved transparency and hardness in α-alumina ceramics fabricated by high-pressure SPS of nanopowders

Effect of cryogenic freezing by liquid nitrogen on the quality and microstructure of Portunus trituberculatus Hori T, Odaka S, Oba H, Mizutani T, Kawakami E, Tsutsui T. Abstract The freezing conditions for preparation of frozen canine semen by the plunging method were investigated with regard to the period of sensitization in liquid nitrogen (LN2) vapor… Continue reading Effect of cryogenic freezing by liquid nitrogen on the quality and microstructure of Portunus trituberculatus

Atmospheric Spray Freeze-Drying: Numerical Modeling and Comparison With Experimental Measurements Israel Borges Sebastião, Thomas D. Robinson, Alina Alexeenko Abstract Atmospheric spray freeze-drying (ASFD) represents a novel approach to dry thermosensitive solutions via sublimation. Tests conducted with a second-generation ASFD equipment, developed for pharmaceutical applications, have focused initially on producing a light, fine, high-grade powder consistently… Continue reading Atmospheric Spray Freeze-Drying: Numerical Modeling and Comparison With Experimental Measurements