Category: Scientific papers

Development of Inhalable Dry Powder Formulations Loaded with Nanoparticles Maintaining Their Original Physical Properties and Functions Okuda T Abstract Functional nanoparticles, such as liposomes and polymeric micelles, are attractive drug delivery systems for solubilization, stabilization, sustained release, prolonged tissue retention, and tissue targeting of various encapsulated drugs. For their clinical application in therapy for pulmonary… Continue reading Development of Inhalable Dry Powder Formulations Loaded with Nanoparticles Maintaining Their Original Physical Properties and Functions

Shrinkage of spray-freeze-dried microparticles of pure protein for ballistic injection by manipulation of freeze-drying cycle Straller G, Lee G Abstract Spray-freeze-drying was used to produce shrivelled, partially-collapsed microparticles of pure proteins that may be suitable for use in a ballistic injector. Various modifications of the freeze drying cycle were examined for their effects on collapse… Continue reading Shrinkage of spray-freeze-dried microparticles of pure protein for ballistic injection by manipulation of freeze-drying cycle

Mechanical particle coating using polymethacrylate nanoparticle agglomerates for the preparation of controlled release fine particles: The relationship between coating performance and the characteristics of various polymethacrylates. Kondo K, Kato S, Niwa T Abstract We aimed to understand the factors controlling mechanical particle coating using polymethacrylate. The relationship between coating performance and the characteristics of polymethacrylate… Continue reading Mechanical particle coating using polymethacrylate nanoparticle agglomerates for the preparation of controlled release fine particles: The relationship between coating performance and the characteristics of various polymethacrylates.

Preparation and Characterization of Pentoxyverine Citrate Micro-Nano Particle Aggregations Bo Chen, Hui Tang, Yong Peng Huang, Jian Lan Jiao, Chuan Pin Zou Abstract Micro-nano drug particle aggregations were prepared by shearing emulsification, high pressure homogenization and spray freeze drying, particle formational process and optimization of preparation conditions were analyzed, and micro-morphologies, particle size distributions, aerodynamic… Continue reading Preparation and Characterization of Pentoxyverine Citrate Micro-Nano Particle Aggregations

Structured emulsion-templated porous copolymer based on photopolymerization for carbon capture Dariush Nikjoo, Farid Akhtar Abstract Porous hydrogel copolymers of acrylamide (AAM) and acrylic acid (AAC) were structured in the form of monoliths and granules. AAM-co-AAC porous copolymer monoliths were synthesized using high internal phase emulsion (HIPE) as template and photopolymerization. For granulation, photopolymerization was used… Continue reading Structured emulsion-templated porous copolymer based on photopolymerization for carbon capture

Phase change and droplet dynamics for a free falling water droplet K.R. Sultana, K. Pope, L.S. Lam, Y.S. Muzychka Abstract This paper numerically examines phase change of free falling droplets in a sub-zero environment. The model is based on the solution of the Navier-Stokes equations coupled with the Volume of Fluid (VOF) methodology for tracking… Continue reading Phase change and droplet dynamics for a free falling water droplet

Improving quercetin dissolution and bioaccessibility with reduced crystallite sizes through media milling technique Muwen Lu, Chi-Tang Ho, Qingrong Huang Abstract Quercetin (QC) is a common bioflavonoid with low water solubility, which limits its oral bioavailability and in vivo beneficial functions. To enhance QC bioaccessibility, QC nanoparticles were produced using the media milling technology. Hydrophobically modified… Continue reading Improving quercetin dissolution and bioaccessibility with reduced crystallite sizes through media milling technique

Solid state stability of polyphenols from a plant extract after fluid bed atmospheric spray-freeze-drying Cristiane Cardoso Correia Teixeira, Tatiana Pereira de Freitas Cabral, Luciana, Alves Tacon, Isabel Lemos Villardi, Aurea Donizete Lanchote, Luis Alexandre Pedro deFreitas Abstract Dry powder extracts are the most suitable pharmaceutical forms of phytomedicines due to their greater physical and chemical… Continue reading Solid state stability of polyphenols from a plant extract after fluid bed atmospheric spray-freeze-drying

Synthesis of high-performance Li2FeSiO4/C composite powder by spray-freezing/freeze-drying a solution with two carbon sources Yukiko Fujita, Hiroaki Iwase, Kenji Shida, Jinsun Liao, Takehisa Fukui, Motohide Matsuda Abstract Li2FeSiO4 is a promising cathode active material for lithium-ion batteries due to its high theoretical capacity. Spray-freezing/freeze-drying, a practical process reported for the synthesis of various ceramic powders,… Continue reading Synthesis of high-performance Li2FeSiO4/C composite powder by spray-freezing/freeze-drying a solution with two carbon sources