Category: Scientific papers

Modern frontiers and applications of spray-freeze-drying in design of food and biological supplements Sayantani Dutta, J. A. Moses, C. Anandharamakrishnan Abstract Spray‐freeze‐drying (SFD) is a unique tandem technique combining spray drying (SD) and freeze drying (FD), and exploiting the advantages of both. SFD is particularly suitable for volatiles, biologicals, and food supplements that are sensitive… Continue reading Modern frontiers and applications of spray-freeze-drying in design of food and biological supplements

Passive inhalation of dry powder influenza vaccine formulations completely protects chickens against H5N1 lethal viral challenge. Tomar J, Biel C, de Haan CAM, Rottier PJM, Petrovsky N, Frijlink HW, Huckriede A, Hinrichs WLJ, Peeters B Abstract Bird to human transmission of high pathogenicity avian influenza virus (HPAIV) poses a significant risk of triggering a flu… Continue reading Passive inhalation of dry powder influenza vaccine formulations completely protects chickens against H5N1 lethal viral challenge.

Effect of Drying Methods of Alumina Powder and Graphene Oxide Mixture on the Mechanical and Electrical Properties of Sintered Composites Fabricated by Spark Plasma Sintering P. V. Fokin, Nestor Washington Solis Pinargote, E. V. Kuznetsova, Pavel Peretyagin Abstract This paper presents a study on graphene-reinforced alumina ceramic composites and the resulting mechanical and electrical properties.… Continue reading Effect of Drying Methods of Alumina Powder and Graphene Oxide Mixture on the Mechanical and Electrical Properties of Sintered Composites Fabricated by Spark Plasma Sintering

Application of disaccharides alone and in combination, for the improvement of stability and particle properties of spray-freeze dried IgG Daneshmand B, Faghihi H, Amini Pouya M, Aghababaie S, Darabi M, Vatanara A Abstract Spray-freeze drying (SFD) is a recently applied method to develop pharmaceutical powders. This study aimed to analyze the competence of Trehalose, Mannitol,… Continue reading Application of disaccharides alone and in combination, for the improvement of stability and particle properties of spray-freeze dried IgG

Advax augments B and T cell responses upon influenza vaccination via the respiratory tract and enables complete protection of mice against lethal influenza virus challenge Tomar J, Patil HP, Bracho G, Tonnis WF, Frijlink HW, Petrovsky N, Vanbever R, Huckriede A, Hinrichs WLJ Abstract Administration of influenza vaccines via the respiratory tract has potential benefits… Continue reading Advax augments B and T cell responses upon influenza vaccination via the respiratory tract and enables complete protection of mice against lethal influenza virus challenge

Using two-fluid nozzle for spray freeze drying to produce porous powder formulation of naked siRNA for inhalation Liang W, Chow MYT, Chow SF, Chan HK, Kwok PCL, Lam JKW Abstract Spray freeze drying is an attractive technology to produce powder formulation for inhalation. It can be used to generate large porous particles which tend to… Continue reading Using two-fluid nozzle for spray freeze drying to produce porous powder formulation of naked siRNA for inhalation.

Processing of sintered and CVD coated SiC/CNFs thin composite tubes Mubina Shaik, Asit Kumar Khanra, Bhaskar Prasad Saha Abstract Silicon carbide (SiC) and its composite powders dispersed with 1–3 wt% carbon nano-fibres (CNFs) were spray freeze granulated to produce spherical granules with uniform composition. Powders were shaped to thin dense tubes for use in a harsh… Continue reading Processing of sintered and CVD coated SiC/CNFs thin composite tubes

Drying Technologies for the Stability and Bioavailability of Biopharmaceuticals Fakhrossadat Emami, Alireza Vatanara, Eun Ji Park, Dong Hee Na Abstract Solid dosage forms of biopharmaceuticals such as therapeutic proteins could provide enhanced bioavailability, improved storage stability, as well as expanded alternatives to parenteral administration. Although numerous drying methods have been used for preparing dried protein… Continue reading Drying Technologies for the Stability and Bioavailability of Biopharmaceuticals

Influence of process variables on physical characteristics of spray freeze dried cellulose nanocrystals Wissam Abdallah, Musa R. Kamal Abstract This study compares the characteristics of cellulose nanocrystal (CNC) agglomerates prepared using spray drying, freeze drying, and spray freeze drying. Moreover, the effect of the concentration of CNC in the initial aqueous dispersion (~ 0.5–10.0 wt%) on… Continue reading Influence of process variables on physical characteristics of spray freeze dried cellulose nanocrystals

Ultrasonic spray-freeze drying of partially purified microbial transglutaminase Hilal Isleroglu, Izzet Turker, Mehmet Tokatli, Banu Koc Abstract Ultrasonic spray-freeze drying (USFD) was evaluated to produce partially purified microbial transglutaminase (mTGase) powder, and the effects of the process conditions (a nozzle frequency of 48–120 kHz and a flow rate of 2–8 ml/min) on enzyme activity and… Continue reading Ultrasonic spray-freeze drying of partially purified microbial transglutaminase