Category: Scientific papers

Dynamical in-situ observation of the lyophilization and vacuum-drying processes of a model biopharmaceutical system by an environmental scanning electron microscope Abstract The paper discusses the real-time monitoring of the changing sample morphology during the entire lyophilization (freeze-drying) and vacuum-drying processes of model biopharmaceutical solutions by using an environmental scanning electron microscope (ESEM); the device’s micromanipulators… Continue reading Dynamical in-situ observation of the lyophilization and vacuum-drying processes of a model biopharmaceutical system by an environmental scanning electron microscope

Sintering investigations of a UO2-PuO2 powder synthesized using the freeze-granulation route Marion Le Guellec, Florent Lebreton, Laure Ramond, Abibatou Ndiaye, Thierry Gervais, Guillaume Bernard-Granger Abstract Sintering investigations of a UO2-PuO2 powder, integrating 11 wt% of PuO2 and synthesized by freeze-granulation, were completed at temperatures up to 1700°C, in an atmosphere of Ar/4 vol% H2 and… Continue reading Sintering investigations of a UO2-PuO2 powder synthesized using the freeze-granulation route

Physicochemical changes of MTGase cross-linked surimi gels subjected to liquid nitrogen spray freezing Xiaoying Luo, Jinling Li, Wenli Yan, Ru Liu, Tao Yin, Juan You, Hongying Du, Shanbai Xiong, Yang Hu Abstract Physicochemical properties of microbial transglutaminase (MTGase) cross-linked surimi gels subjected to liquid nitrogen (LN) spray freezing with different temperatures and cross-linking degrees were… Continue reading Physicochemical changes of MTGase cross-linked surimi gels subjected to liquid nitrogen spray freezing

Effect of formulation and inhaler parameters on the dispersion of spray freeze dried voriconazole particles Qiuying Liao, Ivan C.H. Lam, Hinson H.S. Lin, Leon T.L. Wan, Jason C.K. Lo, Waiting Tai, Philip C.L. Kwok, Jenny K.W. Lam Abstract Spray freeze drying is a particle engineering technique that allows the production of porous particles of low… Continue reading Effect of formulation and inhaler parameters on the dispersion of spray freeze dried voriconazole particles

Evaluation of Process Conditions for Ultrasonic Spray-Freeze Drying of Transglutaminase Hilal İşleroğlu, Izzet Turker Abstract In this study, a commercial transglutaminase enzyme was dried using an ultrasonic spray freeze drying method and the effects of the process conditions were optimized to maximize the final transglutaminase activity. Accordingly, process parameters affecting enzyme activity were selected, such… Continue reading Evaluation of Process Conditions for Ultrasonic Spray-Freeze Drying of Transglutaminase

Developing spray-freeze-dried particles containing a hyaluronic acid-coated liposome–protamine–DNA complex for pulmonary inhalation Kaori Fukushige, Tatsuaki Tagami, Munekazu Naito, Eiichi Goto, Shuichi Hirai, Naoyuki Hatayama, Hiroki Yokota, Takao Yasui, Yoshinobu Baba, Tetsuya Ozeki Abstract The liposome–protamine–DNA complex (LPD) is an effective cationic carrier of various nucleic acid constructs such as plasmid DNA and small interfering RNA… Continue reading Developing spray-freeze-dried particles containing a hyaluronic acid-coated liposome–protamine–DNA complex for pulmonary inhalation

Influences of drying methods on the structural, physicochemical and antioxidant properties of exopolysaccharide from Lactobacillus helveticus MB2-1 Luyao Xiao, Yingying Li, Juanjuan Tian, Jianzhong Zhou, Qian Xu, Li Feng, Xin Rui, Xia Fan, Qiuqin Zhang, Xiaohong Chen, Mingsheng Dong, Wei Li Abstract In this study, in order to evaluate influences of different drying methods on… Continue reading Influences of drying methods on the structural, physicochemical and antioxidant properties of exopolysaccharide from Lactobacillus helveticus MB2-1

Spray-freeze-drying of coffee S. Padma Ishwarya, C. Anandharamakrishnan Abstract The suitability of Spray-Freeze-Drying (SFD) technique for soluble coffee processing was evaluated. The resultant product characteristics were compared against its spray-dried (SD) and freeze-dried (FD) counterparts. SFD and FD coffee powders exhibited a comparable aroma profile as indicated by the electronic nose analysis. SFD resulted in… Continue reading Spray-freeze-drying of coffee

Freeze Granulated Zeolites X and A for Biogas Upgrading Kritika Narang, Farid Akhtar Abstract Biogas is a potential renewable energy resource that can reduce the current energy dependency on fossil fuels. The major limitation of utilizing biogas fully in the various applications is the presence of a significant volume fraction of carbon dioxide in biogas.… Continue reading Freeze Granulated Zeolites X and A for Biogas Upgrading

Effect of encapsulation methods on the physicochemical properties and the stability of Lactobacillus plantarum (NCIM 2083) in synbiotic powders and in-vitro digestion conditions K.S. Yoha, J.A. Moses, C. Anandharamakrishnan Abstract Encapsulation of probiotic bacteria requires precise control over a range of process parameters, all of which are technique-specific. The technology of encapsulation has received considerable… Continue reading Effect of encapsulation methods on the physicochemical properties and the stability of Lactobacillus plantarum (NCIM 2083) in synbiotic powders and in-vitro digestion conditions