Category: Scientific papers

Selectivity of Ru-rich Ru-Ti-O oxide surfaces in parallel oxygen and chlorine evolution reactions Kateřina Minhová Macounová, Rebecca Katharina Pittkowski, Roman Nebel, Andrea Zitolo, Petr Krtil Abstract The electrocatalytic behaviour of single-phase Ru1-xTixO2 materials was studied to outline general trends controlling the selectivity of oxide-based anodes in parallel oxygen evolution and chlorine evolution reactions. Materials with… Continue reading Selectivity of Ru-rich Ru-Ti-O oxide surfaces in parallel oxygen and chlorine evolution reactions

Effects of drying methods on physical properties and morphology of trehalose/mannitol mixtures Daniel Tristan Osanlóo, Jonas Fransson, Björn Bergenståhl, Anna Millqvist-Fureby Abstract Solid-state properties of dried protein formulations are important for stability and functionality of the product. This study investigates how different drying technologies (freeze-drying with and without annealing, spray drying and spray-freeze drying) affect… Continue reading High fine particle fractionEffects of drying methods on physical properties and morphology of trehalose/mannitol mixtures

Micro-fluidic Spray Freeze Dried Ciprofloxacin Hydrochloride-Embedded Dry Powder for Inhalation Yingjie Chen, Shen Yan, Shengyu Zhang, Quanyi Yin, Xiao Dong Chen, Winston Duo Wu Abstract Active pharmaceutical ingredient (API)-embedded dry powder for inhalation (AeDPI) is highly desirable for pulmonary delivery of high-dose drug. Herein, a series of spray freeze-dried (SFD) ciprofloxacin hydrochloride (CH)-embedded dry powders… Continue reading Micro-fluidic Spray Freeze Dried Ciprofloxacin Hydrochloride-Embedded Dry Powder for Inhalation

Solid state of inhalable high dose powders Bishal Raj Adhikari, Keith C. Gordon, Shyamal C. Das Abstract High dose inhaled powders have received increased attention for treating lung infections. These powders can be prepared using techniques such as spray drying, spray-freeze drying, crystallization, and milling. The selected preparation technique is known to influence the solid… Continue reading Solid state of inhalable high dose powders

Effect of spray freeze drying on the structural modification and rehydration characteristics of micellar casein powders Jinbo Ren, Minjie Liao, Lingjun Ma, Fang Chen, Xiaojun Liao, Xiaosong Hu, Song Miao, John Fitzpatrick, Junfu Ji Abstract Micellar casein (MC) is usually spray-dried into powder form for transportation and storage. However, the micellar structure maintained by colloidal… Continue reading Effect of spray freeze drying on the structural modification and rehydration characteristics of micellar casein powders

Ointment containing spray freeze-dried metronidazole effective against rosacea Klára Szentmihályi, Krisztina Móricz, Gábor Gigler, Zoltán May, Eszter Bódis, Judit Tóth, Mónika Bakonyi, Szilvia Klébert, Tivadar Feczkó, Zoltán Károly Abstract Rosacea is a chronic, inflammatory skin disease that affects about 10% of the population. Metronidazole-containing ointments are typically recommended for the daily treatment of symptoms. For… Continue reading Ointment containing spray freeze-dried metronidazole effective against rosace

Microencapsulation of High-Content Actives Using Biodegradable Silk Materials Muchun Liu, Pierre-Eric Millard, Henning Urch, Ophelie Zeyons, Douglas Findley, Rupert Konradi, Benedetto Marelli Abstract There is a compelling need across several industries to substitute non-degradable, intentionally added microplastics with biodegradable alternatives. Nonetheless, stringent performance criteria in actives’ controlled release and manufacturing at scale of emerging materials… Continue reading Microencapsulation of High-Content Actives Using Biodegradable Silk Materials

Spray freeze drying of dairy products: Effect of formulation on dispersibility Alberto Baldelli, Hale Oguzlu, Diana Yumeng Liang, Alison Subiantoro, Meng Wai Woo, Anubhav Pratap-Singh Abstract Milk powders are commonly produced by using the technique of spray drying. In this work, we propose the use of spray freeze drying technology to improve the re-dispersibility of… Continue reading Spray freeze drying of dairy products: Effect of formulation on dispersibility

Spray Freezing Coating on the Carrier Particles for Powder Preparation Qing Xu, Ruixin Wang, Fan Zhang, Ruifang Wang, Long Wu, Bo Lin Abstract Carrier particle spray freeze-drying is a new technology with high added value for thermosensitive powder spray freeze-drying. The technology includes the following steps: atomization, coating, freezing, and drying. Due to the action… Continue reading Spray Freezing Coating on the Carrier Particles for Powder Preparation

Debate: Nanoparticles – a blessing or a curse? Hans Leuenberger Abstract This chapter was inspired by Ilya Prigogine (Nobel laureate 1977) and by six axioms derived1 earlier, such as A1, Far from equilibrium conditions, favoring transformations from disorder into order leading to the creation of life, and A5 and 6, The evolutionary process uses all… Continue reading Debate: Nanoparticles – a blessing or a curse?