Category: Scientific papers

Spray freeze dried lyospheres® for nasal administration of insulin Tuğrul Mert Serim, Jan Kožák, Annika Rautenberg, Ayşe Nurten Özdemir, Yann Pellequer, Alf Lamprecht Abstract Pharmacologically active macromolecules, such as peptides, are still a major challenge in terms of designing a delivery system for their transport across absorption barriers and at the same time provide sufficiently… Continue reading Spray freeze dried lyospheres® for nasal administration of insulin

Intratracheal inoculation of AHc vaccine induces protection against aerosolized botulinum neurotoxin A challenge in mice. Changjiao Gan, Wenbo Luo, Yunzhou Yu, Zhouguang Jiao, Sha Li, Duo Su, Junxia Feng, Xiaodong Zhao, Yefeng Qiu, Lingfei Hu, Dongsheng Zhou, Xiaolu Xiong, Jinglin Wang & Huiying Yang Abstract Botulinum neurotoxin (BoNT), produced by Clostridium botulinum, is generally known… Continue reading Intratracheal inoculation of AHc vaccine induces protection against aerosolized botulinum neurotoxin A challenge in mice.

Inhaled Dry Powder Formulation of Tamibarotene, a Broad-Spectrum Antiviral against Respiratory Viruses Including SARS-CoV-2 and Influenza Virus Qiuying Liao, Shuofeng Yuan, Jianli Cao, Kaiming Tang, Yingshan Qiu, Han Cong Seow, Rico Chi-Hang Man, Zitong Shao, Yaoqiang Huang, Ronghui Liang, Jasper Fuk-Woo Chan, Kwok-Yung Yuen, Jenny Ka-Wing Lam Abstract In response to the epidemic and pandemic… Continue reading Inhaled Dry Powder Formulation of Tamibarotene, a Broad-Spectrum Antiviral against Respiratory Viruses Including SARS-CoV-2 and Influenza Virus

Comparative Study on Compaction and Sintering Behavior of Spray and Freeze Granulated Magnesium Aluminate Spinel Powder Swathi Manivannan, Papiya Biswas, Prasenjit Barick, Sweety Kumari, Bhaskar Prasad Saha & Roy Johnson Abstract Commercially procured magnesium aluminate (MgAl2O4) spinel powder with average particle size of 300 nm and irregular morphology were spray and freeze granulated. The granules… Continue reading Comparative Study on Compaction and Sintering Behavior of Spray and Freeze Granulated Magnesium Aluminate Spinel Powder

Morphology of alumina granules obtained by spray freeze drying with twin-fluid atomization Ruslan Kuzmin, Sergey Veselov, Nina Cherkasova, Vladimir Bataev Abstract This study presents the results of the morphological dependence of alumina granules obtained by spray freeze drying (SFD) with twin-fluid atomization. It is shown that the introduction of 1-, 2- and 4-wt.% polyvinyl alcohol… Continue reading Morphology of alumina granules obtained by spray freeze drying with twin-fluid atomization

Combination of copigmentation and encapsulation strategies for the synergistic stabilization of anthocyanins Chen Tan, Younas Dadmohammadi, Michelle C. Lee, Alireza Abbaspourrad Abstract Copigmentation and encapsulation are the two most commonly used techniques for anthocyanin stabilization. However, each of these techniques by itself suffers from many challenges associated with the simultaneous achievement of color intensification and… Continue reading Combination of copigmentation and encapsulation strategies for the synergistic stabilization of anthocyanins

Effect of drying techniques on yield, nutritional, minerals of wild banana pulp (Musa balbisiana Colla): physicochemical and morphological characterization thereof Twinkle Borah, Nooreen Washmin, Nayan Jyoti Bora, Jadumoni Saikia, Padma Sangmu Bomzon, Tobiul Hussain Ahmed, Prasenjit Manna, Siddhartha Proteem Saikia, Dipanwita Banik Abstract Purpose The study was aimed to compare the effect of three drying… Continue reading Effect of drying techniques on yield, nutritional, minerals of wild banana pulp (Musa balbisiana Colla): physicochemical and morphological characterization thereof

Thermolysis and Sensitivities of Nanometer Ammonium Nitrate Prepared by Ultra-low Temperature Spray Freeze Drying Method Yi Wang, Xiaolan Song, Fengsheng Li Abstract Nanometer (nano) ammonium perchlorate (AP) and ammonium nitrate (AN) were prepared with 2D network structures by the ultra-low temperature spray method. Scanning electron microscopy (SEM), X-ray diffractometry (XRD), differential scanning calorimetry (DSC) and… Continue reading Thermolysis and Sensitivities of Nanometer Ammonium Nitrate Prepared by Ultra-low Temperature Spray Freeze Drying Method

Effects of Non-covalent Functionalization and Initial Mixing Methods on SWNT/PP and SWNT/EVOH Composites Mahesh Parit, Virginia A. Davis Abstract We report that a simple, low-cost type of spray-freeze drying (SFD) significantly improves the dispersion of single-walled carbon nanotubes (SWNTs) in thermoplastic polymers. Conventional SFD requires costly specialized equipment and large amounts of material, both of… Continue reading Effects of Non-covalent Functionalization and Initial Mixing Methods on SWNT/PP and SWNT/EVOH Composites

Inhalable Protein Powder Prepared by Spray-Freeze-Drying Using Hydroxypropyl-β-Cyclodextrin as Excipient Jason C. K. Lo, Harry W. Pan, Jenny K. W. Lam Abstract The prospect of inhaled biologics has garnered particular interest given the benefits of the pulmonary route of administration. Pertinent considerations in producing inhalable dry powders containing biological medicines relate to aerosol performance and… Continue reading Inhalable Protein Powder Prepared by Spray-Freeze-Drying Using Hydroxypropyl-β-Cyclodextrin as Excipient