Category: Scientific papers

Freeze granulation and spray drying of mixed granules of Al2O3 M. Singlard, A. Paillassa, L. Ferres, C. Pagnoux, A. Aimable Abstract This paper proposes a comparative study of two techniques of granulation of a submicronic alumina powder with high binder content slurries, by spray drying and freeze granulation for the preparation of mixed granules. First,… Continue reading Freeze granulation and spray drying of mixed granules of Al2O3

Freeze Granulation of Nanoporous UiO-66 Nanoparticles for Capture of Volatile Organic Compounds Van Nhieu Le, Daekeun Kim, Jinsoo Kim, Mohd Roslee Othman Abstract Nanoporous UiO-66 spherical beads prepared by using PVA binder successfully connected UiO-66 nanoparticles together into granular beads with improved mechanical strength for toluene capture. This was achieved without affecting the crystalline nature… Continue reading Freeze Granulation of Nanoporous UiO-66 Nanoparticles for Capture of Volatile Organic Compounds

Maximizing the enzyme immobilization of enzymatic glucose biofuel cells through hierarchically structured reduced graphene oxide Joonyoung Lee, Kyuhwan Hyun, Jae Min Park, Ho Seok Park, Yongchai Kwon Summary The number of immobilized glucose oxidase (GOx) molecules is considerably increased by the structural modification of reduced graphene oxide (rGO), and the performance of enzymatic biofuel cells… Continue reading Maximizing the enzyme immobilization of enzymatic glucose biofuel cells through hierarchically structured reduced graphene oxide

Improvement of Drug Delivery Properties of Risperidone via Preparation of Oral Disintegration Tablet Containing Nanostructured Microparticles Motahare salarvanda, Zeinab Aref Darabi, Vahid Ramezani Abstract Introduction: The aim of this study was to improve the dissolution profile of risperidone and increase the compliance of psychotic patients through the design of an oral disintegration tablet­ (ODT) of… Continue reading Improvement of Drug Delivery Properties of Risperidone via Preparation of Oral Disintegration Tablet Containing Nanostructured Microparticles

Post-Processing Techniques for the Improvement of Liposome Stability Ji Young Yu, Piyanan Chuesiang, Gye Hwa Shin, Hyun Jin Park Abstract Liposomes have been utilized as a drug delivery system to increase the bioavailability of drugs and to control the rate of drug release at the target site of action. However, the occurrence of self-aggregation, coalescence,… Continue reading Post-Processing Techniques for the Improvement of Liposome Stability

Influence of the PuO2 content on the sintering behaviour of UO2-PuO2 freeze-granulated powders under reducing conditions Julie Simeon, Florent Lebreton, Laure Ramond, Nicolas Clavier, Guillaume Bernard-Granger Abstract The sintering behaviour of freeze-granulated UO2-PuO2 powders containing 33 and 15 mol% Pu/(U + Pu) was investigated under reducing conditions up to 1700 °C. For both compositions, the… Continue reading Influence of the PuO2 content on the sintering behaviour of UO2-PuO2 freeze-granulated powders under reducing conditions

Mixed bacteriophage ms2-l2 vlps elicit long-lasting protective antibodies against hpv pseudovirus 51 Abstract Three prophylactic vaccines are approved to protect against HPV infections. These vaccines are highly immunogenic. The most recent HPV vaccine, Gardasil-9, protects against HPV types associated with ~90% of cervical cancer (worldwide). Thus, ~10% of HPV-associated cancers are not protected by Gardasil-9.… Continue reading Mixed bacteriophage ms2-l2 vlps elicit long-lasting protective antibodies against hpv pseudovirus 51

Spray freeze dried lyospheres® for nasal administration of insulin Tuğrul Mert Serim, Jan Kožák, Annika Rautenberg, Ayşe Nurten Özdemir, Yann Pellequer, Alf Lamprecht Abstract Pharmacologically active macromolecules, such as peptides, are still a major challenge in terms of designing a delivery system for their transport across absorption barriers and at the same time provide sufficiently… Continue reading Spray freeze dried lyospheres® for nasal administration of insulin

Intratracheal inoculation of AHc vaccine induces protection against aerosolized botulinum neurotoxin A challenge in mice. Changjiao Gan, Wenbo Luo, Yunzhou Yu, Zhouguang Jiao, Sha Li, Duo Su, Junxia Feng, Xiaodong Zhao, Yefeng Qiu, Lingfei Hu, Dongsheng Zhou, Xiaolu Xiong, Jinglin Wang & Huiying Yang Abstract Botulinum neurotoxin (BoNT), produced by Clostridium botulinum, is generally known… Continue reading Intratracheal inoculation of AHc vaccine induces protection against aerosolized botulinum neurotoxin A challenge in mice.

Inhaled Dry Powder Formulation of Tamibarotene, a Broad-Spectrum Antiviral against Respiratory Viruses Including SARS-CoV-2 and Influenza Virus Qiuying Liao, Shuofeng Yuan, Jianli Cao, Kaiming Tang, Yingshan Qiu, Han Cong Seow, Rico Chi-Hang Man, Zitong Shao, Yaoqiang Huang, Ronghui Liang, Jasper Fuk-Woo Chan, Kwok-Yung Yuen, Jenny Ka-Wing Lam Abstract In response to the epidemic and pandemic… Continue reading Inhaled Dry Powder Formulation of Tamibarotene, a Broad-Spectrum Antiviral against Respiratory Viruses Including SARS-CoV-2 and Influenza Virus