Spray freeze dried uniform mannitol microspheres Shen Yan, Shengyu Zhang, Xiao Dong Chen, Winston Duo Wu Abstract Spray freeze drying is an attractive technology for fabricating pharmaceutical powder, but it is still challenging to tailor the microparticle physical and chemical structure. Herein, a series of uniform mannitol microparticles with controllable morphology and crystal properties were… Continue reading Spray freeze dried uniform mannitol microspheres
Category: Scientific papers
Spray-freeze-drying as emerging and substantial quality enhancement technique in food industry
Spray-freeze-drying as emerging and substantial quality enhancement technique in food industry Poornima Singh, Vinay Kumar Pandey, Rahul Singh, Aamir Hussain Dar Abstract Spray freeze drying is an emerging technology in the food industry with numerous applications. Its ability to preserve food quality, maintain nutritional value, and reduce bulk make it an attractive option to food… Continue reading Spray-freeze-drying as emerging and substantial quality enhancement technique in food industry
Spray Freeze Drying of Biologics: A Review and Applications for Inhalation Delivery
Spray Freeze Drying of Biologics: A Review and Applications for Inhalation Delivery Susana Farinha, João V Sá, Paulo Roque Lino, Marco Galésio, João Pires, Miguel Ângelo Rodrigues, João Henriques Abstract Biopharmaceuticals have established an indisputable presence in the pharmaceutical pipeline, enabling highly specific new therapies. However, manufacturing, isolating, and delivering these highly complex molecules to… Continue reading Spray Freeze Drying of Biologics: A Review and Applications for Inhalation Delivery
Granulation of fine eggshell powder to produce feedstock powder for binder jetting additive manufacturing: A feasibility study
Granulation of fine eggshell powder to produce feedstock powder for binder jetting additive manufacturing: A feasibility study Shakil Arman, Fahim Khan, Mostafa Meraj Pasha, Jackson Sanders, Zhijian Pei Abstract This paper explores the feasibility of granulating fine eggshell powder using spray freeze drying to produce feedstock powder for binder jetting additive manufacturing. Fine eggshell powder possesses carbon-capture potential but exhibits poor flowability, causing issues during powder spreading in binder jetting additive… Continue reading Granulation of fine eggshell powder to produce feedstock powder for binder jetting additive manufacturing: A feasibility study
A Comprehensive Review of the Latest Trends in Spray Freeze Drying and Comparative Insights with Conventional Technologies
A Comprehensive Review of the Latest Trends in Spray Freeze Drying and Comparative Insights with Conventional Technologies Maria Ioannou Sartzi, Dimitrios Drettas, Marina Stramarkou and Magdalini Krokida Abstract Spray freeze drying (SFD) represents an emerging drying technique designed to produce a wide range of pharmaceuticals, foods, and active components with high quality and enhanced stability… Continue reading A Comprehensive Review of the Latest Trends in Spray Freeze Drying and Comparative Insights with Conventional Technologies
Porous silicon nitride–based drug delivery carrier
Porous silicon nitride–based drug delivery carrier Michal Hičák, Ľubomír Medvecký, Miroslav Hnatko, Radoslava Stulajterová, Mária Giretová, Monika Tatarková, Zoltán Lenčéš, Pavol Šajgalík Abstract Tetracalcium phosphate/monetite biocement was modified with the addition of 30 wt% highly porous silicon nitride/α-tricalcium phosphate (α-TCP) microgranules. The volume ratio of Si3N4 and α-TCP in microgranules was 1:1 and showed good… Continue reading Porous silicon nitride–based drug delivery carrier
Physical properties of feeds for novel bioactives – encapsulating bead formation
Physical properties of feeds for novel bioactives – encapsulating bead formation Hansen, Mackenzie M. Abstract Encapsulation involves the entrapment of sensitive bioactive compounds with structure- forming food components to enhance protection and delivery. Blends of proteins and glass- forming carbohydrates are often used as encapsulation matrices and for structure formation. When bioactives intended for encapsulation… Continue reading Physical properties of feeds for novel bioactives – encapsulating bead formation
Sintering and microstructure development of SFR MOX nuclear fuel
Sintering and microstructure development of SFR MOX nuclear fuel Julie Simeon Abstract For the manufacture of FNR (Fast Neutron Reactor) MOX (Mixed Oxide) fuel, (U,Pu)O2-x, consolidation of green compacts shaped from the raw powders, is performed by sintering at high temperature. Thus, the detailed study of the sintering is based on coupling of dilatometric tests… Continue reading Sintering and microstructure development of SFR MOX nuclear fuel
Formation of dry beads for bioactives encapsulation by freeze granulation
Formation of dry beads for bioactives encapsulation by freeze granulation Mackenzie M. Hansen, Richard W. Hartel, Yrjö H. Roos Abstract Solid beads formed by whey protein isolate (WPI) and various sugars/polyols with a wide range of glass transition temperatures showed potential as structures for encapsulation of Aronia berry bioactives. Whey protein isolate (WPI), Aronia extract,… Continue reading Formation of dry beads for bioactives encapsulation by freeze granulation
Porous silicon nitride-based drug delivery carrier
Porous silicon nitride-based drug delivery carrier Hicak, Michal; Medvecky, L’ubomir; Hnatko, Miroslav; Stulajterova, Radoslava; Giretova, Maria; Tatarkova, Monika; Lences, Zoltan; Sajgalik, Pavol Abstract Tetracalcium phosphate/monetite biocement was modified with the addition of 30 wt% highly porous silicon nitride/alpha-tricalcium phosphate (alpha-TCP) microgranules. The volume ratio of Si3N4 and alpha-TCP in microgranules was 1:1 and showed good… Continue reading Porous silicon nitride-based drug delivery carrier