Improved transparency and hardness in α-alumina ceramics fabricated by high-pressure SPS of nanopowders

Improved transparency and hardness in α-alumina ceramics fabricated by high-pressure SPS of nanopowders Shaghayegh Ghanizadeha, Salvatore Grassob, Prabhu Ramanujamc, Bala Vaidhyanathana, Jon Binnerc, Peter Brownd, Judah Goldwassere Abstract Nanocrystalline alumina powder with an average crystallite size of ≤50 nm has been consolidated by spark plasma sintering (SPS) and hot pressing (HP) with a view to… Continue reading Improved transparency and hardness in α-alumina ceramics fabricated by high-pressure SPS of nanopowders

Effect of cryogenic freezing by liquid nitrogen on the quality and microstructure of Portunus trituberculatus

Effect of cryogenic freezing by liquid nitrogen on the quality and microstructure of Portunus trituberculatus Hori T, Odaka S, Oba H, Mizutani T, Kawakami E, Tsutsui T. Abstract The freezing conditions for preparation of frozen canine semen by the plunging method were investigated with regard to the period of sensitization in liquid nitrogen (LN2) vapor… Continue reading Effect of cryogenic freezing by liquid nitrogen on the quality and microstructure of Portunus trituberculatus

Atmospheric Spray Freeze-Drying: Numerical Modeling and Comparison With Experimental Measurements

Atmospheric Spray Freeze-Drying: Numerical Modeling and Comparison With Experimental Measurements Israel Borges Sebastião, Thomas D. Robinson, Alina Alexeenko Abstract Atmospheric spray freeze-drying (ASFD) represents a novel approach to dry thermosensitive solutions via sublimation. Tests conducted with a second-generation ASFD equipment, developed for pharmaceutical applications, have focused initially on producing a light, fine, high-grade powder consistently… Continue reading Atmospheric Spray Freeze-Drying: Numerical Modeling and Comparison With Experimental Measurements

Hydroxypropylcellulose as matrix carrier for novel cage-like microparticles prepared by spray-freeze-drying technology

Hydroxypropylcellulose as matrix carrier for novel cage-like microparticles prepared by spray-freeze-drying technology Shaofeng Weia, Yueqin Mab, Jing Luoa, Xiaoru Hea, Pengfei Yuea, Zhiyu Guana, Ming Yanga Abstract The objective of this study is to design novel dissolution-enhanced microparticles loaded poorly soluble drug nanocrystals used a low viscosity of hydroxypropylcellulose (HPC) as matrix carrier. An interesting… Continue reading Hydroxypropylcellulose as matrix carrier for novel cage-like microparticles prepared by spray-freeze-drying technology

Additive-free hot-pressed silicon carbide ceramics-A material with exceptional mechanical properties

Additive-free hot-pressed silicon carbide ceramics-A material with exceptional mechanical properties P. Šajgalík, J. Sedláček, Z. Lenčéš, J. Dusza, H.-T. Lin Abstract Densification of silicon carbide without any sintering aids by hot-pressing and rapid hot pressing was investigated. Full density (>99% t.d.) has been reached at 1850 °C, a temperature of at least 150–200 °C lower compared to… Continue reading Additive-free hot-pressed silicon carbide ceramics-A material with exceptional mechanical properties

Dry powder formulation of plasmid DNA and siRNA for inhalation

Dry powder formulation of plasmid DNA and siRNA for inhalation Chow MY, Lam JK Abstract Nucleic acid therapeutics has huge potential for the treatment of a wide range of diseases including respiratory diseases. Plasmid DNA (pDNA) and small interfering RNA (siRNA) are the two most widely investigated nucleic acids for therapeutic development. However, efficient and… Continue reading Dry powder formulation of plasmid DNA and siRNA for inhalation

Dry powder inhaler formulation of high-payload antibiotic nanoparticle complex intended for bronchiectasis therapy: Spray drying versus spray freeze drying preparation

Dry powder inhaler formulation of high-payload antibiotic nanoparticle complex intended for bronchiectasis therapy: Spray drying versus spray freeze drying preparation Yu H, Teo J, Chew JW, Hadinoto K Abstract Inhaled nano-antibiotics have recently emerged as the promising bronchiectasis treatment attributed to the higher and more localized antibiotic exposure generated compared to native antibiotics. Antibiotic nanoparticle… Continue reading Dry powder inhaler formulation of high-payload antibiotic nanoparticle complex intended for bronchiectasis therapy: Spray drying versus spray freeze drying preparation

Spray Freeze-Drying as an Alternative to the Ionic Gelation Method to Produce Chitosan and Alginate Nano-Particles Targeted to the Colon

Spray Freeze-Drying as an Alternative to the Ionic Gelation Method to Produce Chitosan and Alginate Nano-Particles Targeted to the Colon Gamboa A, Araujo V, Caro N, Gotteland M, Abugoch L, Tapia C Abstract Chitosan and alginate nano-composite (NP) carriers intended for colonic delivery containing prednisolone and inulin were obtained by two processes. Spray freeze-drying using… Continue reading Spray Freeze-Drying as an Alternative to the Ionic Gelation Method to Produce Chitosan and Alginate Nano-Particles Targeted to the Colon

Mass production of graphene nanoscrolls and their application in high rate performance supercapacitors

Mass production of graphene nanoscrolls and their application in high rate performance supercapacitors Bingna Zheng,   Zhen Xu and   Chao Gao The output of graphene nanoscrolls (GNSs) has been greatly enhanced to the gram-level by using an improved spray-freeze-drying method without damaging the high transforming efficiency (>92%). The lowest bulk density of GNS foam reaches 0.10… Continue reading Mass production of graphene nanoscrolls and their application in high rate performance supercapacitors

Production of Inhalation Phage Powders Using Spray Freeze Drying and Spray Drying Techniques for Treatment of Respiratory Infections

Production of Inhalation Phage Powders Using Spray Freeze Drying and Spray Drying Techniques for Treatment of Respiratory Infections Leung SS, Parumasivam T, Gao FG, Carrigy NB, Vehring R, Finlay WH, Morales S, Britton WJ, Kutter E, Chan HK Abstract PURPOSE: The potential of aerosol phage therapy for treating lung infections has been demonstrated in animal… Continue reading Production of Inhalation Phage Powders Using Spray Freeze Drying and Spray Drying Techniques for Treatment of Respiratory Infections