Category: Scientific papers

Production of bromelain aerosols using spray-freeze-drying technique for pulmonary supplementation M. N. Lavanya, R. Preethi, J. A. Moses, C. Anandharamakrishnan Abstract Spray-freeze-drying (SFD) is a promising technique to produce inhalable dry powder formulations that able to retain the integrity of bioactive compounds. Therefore, in this study bromelain aerosols were developed using SFD by varying core-to-wall… Continue reading Production of bromelain aerosols using spray-freeze-drying technique for pulmonary supplementation

Fabrication and microstructure analysis of continuous C fibers reinforced SiC-Cnfs hybrid composite tubes Shaik Mubina, M. Ilaiyaraja, Asit Kumar Khanra, Bhaskar Prasad Saha Abstract The carbon nanofibers (Cnfs) dispersed SiC-Cnfs composite powder has been produced by spray freeze-granulation technique. SiC-based hybrid composite tubes (BN-Cf/SiC-Cnfs) were fabricated by systematically laying of boron nitride-coated continuous carbon fiber… Continue reading Fabrication and microstructure analysis of continuous C fibers reinforced SiC-Cnfs hybrid composite tubes

Comparison of Strategies in Development and Manufacturing of Low Viscosity, Ultra-High Concentration Formulation for IgG1 Antibody Vaibhav Deokar, Alok Sharma, Rustom Mody, Subrahmanyam M. Volety Abstract Monoclonal antibodies requiring higher doses for exerting therapeutic effect but having lower stability, are administered as dilute infusions, or as two (low concentration) injections both resulting in reduced patient… Continue reading Comparison of Strategies in Development and Manufacturing of Low Viscosity, Ultra-High Concentration Formulation for IgG1 Antibody

Targeted Pulmonary Delivery of the Green Tea Polyphenol Epigallocatechin Gallate Controls the Growth of Mycobacterium tuberculosis by Enhancing the Autophagy and Suppressing Bacterial Burden Ankur Sharma, Kalpesh Vaghasiya, Eupa Ray, Pushpa Gupta, Umesh Datta Gupta, Amit Kumar Singh, Rahul Kumar Verma Abstract Growing rates of tuberculosis (TB) superbugs are alarming, which has hampered the progress… Continue reading Targeted Pulmonary Delivery of the Green Tea Polyphenol Epigallocatechin Gallate Controls the Growth of Mycobacterium tuberculosis by Enhancing the Autophagy and Suppressing Bacterial Burden

Drying of Vaccines and Biomolecules Bhaskar N. Thorat Institute of Chemical Technology, Bhubaneswar, India Correspondencebn.thorat@ictmumbai.edu.in, Ayantika Sett Department of Chemical Engineering, Institute of Chemical Technology, Bhubaneswar, India & A. S. Mujumdar Institute of Chemical Technology, Matunga(E), Mumbai, India Abstract Vaccines are the most important life-saving prophylactic medicines administered in maintaining global health. In a pandemic… Continue reading Drying of Vaccines and Biomolecules

Ceramic binder jetting additive manufacturing: Effects of granulation on properties of feedstock powder and printed and sintered parts Guanxiong Miao, Wenchao Du, Mohammadamin Moghadasi, Zhijian Pei, Chao Ma Abstract Because of its high sinterability, nanopowder could be beneficial for ceramic binder jetting additive manufacturing to achieve a high density on printed and sintered parts. However,… Continue reading Ceramic binder jetting additive manufacturing: Effects of granulation on properties of feedstock powder and printed and sintered parts

Stability of Instant Coffee Foam by Nanobubbles Using Spray-Freeze Drying Technique Abstract Instant coffee with stable foam is considered to be an important parameter for consumer preference and acceptability. For foam sustenance, nanoscale bubbles are more useful compared with microbubbles, due to their high specific area and high stagnation in the liquid phase (without undesirable… Continue reading Stability of Instant Coffee Foam by Nanobubbles Using Spray-Freeze Drying Technique

Desalination of seawater by spray freezing in a natural draft tower YangLiu, TingzhenMing, YongjiaWu, Renaudde Richter, YuepingFang, NanZhou Abstract The freeze-melting process can be a viable method for the purposes of desalination because of its low energy consumption, ignorable corrosion issues, and without huge pressure or membrane replacement work. Large contact area for heat and… Continue reading Desalination of seawater by spray freezing in a natural draft tower

Inhalable nanoparticulate powders for respiratory delivery Priya Muralidharan, Monica Malapit, Evan Mallory, Don Hayes Jr., Heidi M. Mansour Abstract Nanoparticles are extensively studied for drug delivery and are proving to be effective in drug delivery and the diagnostic field. Drug delivery to lungs has its advantages over other routes of administration. Inhalable powders consisting of… Continue reading Inhalable nanoparticulate powders for respiratory delivery

Impact of excipient choice on the aerodynamic performance of inhalable spray-freeze-dried powders Stefan Wanning, Richard Süverkrüp, Alf Lamprecht Abstract Spray-freeze-drying (SFD) is a process in which a solution is dispersed into a freezing medium and dried by sublimation, resulting in lyophilized powders with spherical particles. This study aims at screening and evaluating the impact of… Continue reading Impact of excipient choice on the aerodynamic performance of inhalable spray-freeze-dried powders