Category: Scientific papers

Design and DEM simulation analysis of the rotary freeze dryer in dynamic spray freeze-drying equipment Runling Peng ,Zhan Gao, Haonan Zhai, Jinyue Liu, Wei Wang, Jinjuan Sun, Yunbo Shen Abstract For spray freeze-drying (SFD) powder materials, traditional static drying is not conducive to heat and mass transfer due to the accumulation of dried layers, resulting… Continue reading Design and DEM simulation analysis of the rotary freeze dryer in dynamic spray freeze-drying equipment

Effects of spray freeze drying and pulsed electric fields on fenugreek seed extract properties Butti Prabhakar, Raghupatruni Venkateswara Prasad Abstract Plant extracts are increasingly recognized for their potential health benefits, creating a growing demand for efficient extraction and preservation methods. In this study, a pulsed electric field (PEF) system was applied to maximize the extraction… Continue reading Effects of spray freeze drying and pulsed electric fields on fenugreek seed extract properties

An Innovative Formulation Development Approach of Sustained Release Matrix Tablet: A Review S Gokulakrishnan, K. B. Ilango, Kalyan R, R Samyuktha, A Subash, K Subhashini Abstract This review delves about the various manufacturing process/ method of the sustained release matrix tablet & the methods are direct compression, wet granulation, dry granulation, foam granulation, freeze granulation,… Continue reading An Innovative Formulation Development Approach of Sustained Release Matrix Tablet: A Review

Freeze-Drying Granulation of Non-Aqueous Nitride Slurry Riko YAMAZAKI , Junichi TATAMI Abstract To apply the spray freeze granulation drying technique for nitride fabrication, we prepared silicon nitride slurries using a mixture of tert-butyl alcohol and cyclohexane as a solvent and attempted to understand the internal structural changes of the slurries by observing their freezing behavior.… Continue reading Freeze-Drying Granulation of Non-Aqueous Nitride Slurry

A Review of Recent Techniques for Granulation Thalari Sravani Abstract Granulation is the process of designing particles by combining primary power particles into massive multiparticle structures known as granules. Its primary purposes are to boost the flow of power, prevent segregation, improve the compaction characteristics of mix uniformity, and improve the flow and compressibility of… Continue reading A Review of Recent Techniques for Granulation

Fabrication of hollow MgO granules via freeze granulation as a filler for lightweight thermal interface materials Rokhyeon Kim, Yunha Lee, Joo-Hwan Han, Chee-Sung Park & Jungho Ryu Abstract With the improvement in the performance of electric vehicles (EVs), heat generation by the battery increases, potentially leading to a number of issues; thus, the thermal management… Continue reading Fabrication of hollow MgO granules via freeze granulation as a filler for lightweight thermal interface materials

An Innovative Formulation Development Approach of Sustained Release Matrix Tablet: A Review S Gokulakrishnan, K B Ilango, R Kalyan, R Samyuktha, A Subash, K Subhashini Abstract This review delves about the various manufacturing process/ method of the sustained release matrix tablet & the methods are direct compression, wet granulation, dry granulation, foam granulation, freeze granulation,… Continue reading An Innovative Formulation Development Approach of Sustained Release Matrix Tablet: A Review

Development of spray freezer for production of freeze granulations DARSHAN M B , ABHIJIT KAR , DEBABANDYA MOHAPATRA Abstract Spray freezer is an essential component of spray freeze drying (SFD) technique to produce microspheres during encapsulation. In this study, a lab scale spray freezer unit was developed to produce freeze granulations, which could be used… Continue reading Development of spray freezer for production of freeze granulations

Systematic investigation of thermal process parameters on the morphology of spray-freeze-dried powders Annika Rautenberg, José Ignacio Vázquez-Olvera, Paul Bühlbecker, Alf Lamprecht Abstract Hypothesis: During spray freeze drying (SFD), vitrification, recrystallization, and polymorphic transitions govern particle morphology and mechanical integrity. We hypothesize that with control over freezing temperature, annealing relative to the glass transition of the maximally… Continue reading Systematic investigation of thermal process parameters on the morphology of spray-freeze-dried powders

SPRAY FREEZE DRYING FORMATION OF DRY POWDER COMPOSITIONS Inventors: BUCKLAND, JustinCHATURBEDY, PiyushTAYLOR, SteveWENBAN, NathanCOUPLAND, George Abstract The present invention relates to dry powder compositions, methods, apparatus and systems for manufacture of the same. In particular, the present invention relates to a system for producing a dry powder composition including a vacuum chamber depressurised by a… Continue reading SPRAY FREEZE DRYING FORMATION OF DRY POWDER COMPOSITIONS