Category: Scientific papers

Spray Freeze Drying Equipment Unlocking Growth Potential: Analysis and Forecasts 2025-2033 Key Insights The spray freeze drying equipment market is experiencing robust growth, driven by increasing demand across various sectors, including pharmaceuticals, biotechnology, and food processing. The market size in 2025 is estimated at $500 million, projected to grow at a Compound Annual Growth Rate… Continue reading Spray Freeze Drying Equipment Unlocking Growth Potential: Analysis and Forecasts 2025-2033

Beyond Traditional Methods: Novel Granulation Approaches for Enhanced Functionality in Pharmaceuticals Ch. Niranjan Patra*, Supriyo Satapathy, Shuvendu K Dinda, Sudarsan Behera, Sashank S Hota, Goutam K Jena and Sanjiv K Panda Abstract Granulation, a cornerstone process in many industries, has seen significant advancements in recent years. This abstract explores these novel techniques, highlighting their potential… Continue reading Beyond Traditional Methods: Novel Granulation Approaches for Enhanced Functionality in Pharmaceuticals

Full Density Powder Metallurgical Cold Work Tool Steel through Nitrogen Sintering and Capsule-Free Hot Isostatic Pressing Anok Babu Nagaram, Giulio Maistro, Erik Adolfsson, Yu Cao, Eduard Hryha and Lars Nyborg Abstract Vanadis 4E (V4E) is a powder metallurgical cold work tool steel predominantly used in application with demand for wear resistance, high hardness, and toughness.… Continue reading Full Density Powder Metallurgical Cold Work Tool Steel through Nitrogen Sintering and Capsule-Free Hot Isostatic Pressing

Advances in Spray-Drying and Freeze-Drying Technologies for the Microencapsulation of Instant Tea and Herbal Powders: The Role of Wall Materials Júlia Mazár, Krisztina Albert ,Zoltán Kovács , András Koris, Arijit Nath and Szilvia Bánvölgyi Abstract The microencapsulation of tea and herbal extracts is gaining considerable attention in the food industry, particularly in the production of… Continue reading Advances in Spray-Drying and Freeze-Drying Technologies for the Microencapsulation of Instant Tea and Herbal Powders: The Role of Wall Materials

METHOD FOR PRODUCING GRANULES, METHOD FOR PRODUCING NITRIDE CERAMIC SINTERED COMPACT, AND GRANULES Inventors高浪　健太郎 TAKANAMI, Kentaro宮本　翔子 MIYAMOTO, Shoko伊藤　和弘 ITO, Kazuhiro矢久保　怜奈 YAKUBO, Reina Abstract Provided is a method for producing granules comprising granulation of a slurry containing a nitride ceramic powder, a sintering agent, an aqueous solvent and an organic additive by spray freeze granulation drying.

Binder Jetting Additive Manufacturing of Ceramics: Feedstock Powder Preparation by Spray Freeze Granulation Wenchao Mark Du, Guanxiong Miao, Lianlian Liu, Z.J. Pei, Chao Ma Abstract Objective of this study is to prepare the binder jetting feedstock powder by spray freeze drying and study the effects of its parameters on the powder properties. Binder jetting additive… Continue reading Binder Jetting Additive Manufacturing of Ceramics: Feedstock Powder Preparation by Spray Freeze Granulation

ASEPTIC SPRAY FREEZE DRYING AS A TOOL FOR SUPPLY CHAIN FLEXIBILISATION F. Kongoli, S. Buchmann, G. Imanidis, I. Karim, G. Kimura, G. Knipp, M. Makanga, N. Menshutina, P. Swaan, M. Tanner, H. Tarabishi Abstract Spray Freeze Drying (SFD) is an innovative lyophilization technology that is now entering industrial applications in lab, pilot and manufacturing scale… Continue reading ASEPTIC SPRAY FREEZE DRYING AS A TOOL FOR SUPPLY CHAIN FLEXIBILISATION

Lowering compaction pressure and sintering temperature of alumina using spray freeze granulation dried granules Naoki Kondo1, Akihiro Shimamura, Mikinori Hotta, Junichi Tatami and Shinya Kawaguchi Abstract Spray drying (SD) and spray freeze granulation drying (SFGD) are the granulation processes of ceramic powder. Alumina green body made from SFGD granules via compaction has a relatively uniform… Continue reading Lowering compaction pressure and sintering temperature of alumina using spray freeze granulation dried granules

Effect of spray freeze drying on the structural modification and rehydration characteristics of micellar casein powders Jinbo Ren, Minjie Liao, Lingjun Ma, Fang Chen, Xiaojun Liao, Xiaosong Hu, Song Miao, John Fitzpatrick, Junfu Ji Abstract Micellar casein (MC) is usually spray-dried into powder form for transportation and storage. However, the micellar structure maintained by colloidal calcium phosphate (CCP) and hydrophobic forces leads to poor rehydration ability of MC powders, which limits its… Continue reading Effect of spray freeze drying on the structural modification and rehydration characteristics of micellar casein powders

Stable and inhalable powder formulation of mRNA-LNPs using pH-modified spray-freeze drying Koki Ogawa, Otowa Aikawa, Tatsuaki Tagami, Takaaki Ito, Kohei Tahara, Shigeru Kawakami, Tetsuya Ozeki Abstract A powder formulation for mucosal administration of mRNA-encapsulated lipid nanoparticles (mRNA-LNPs) is expected to be useful for respiratory diseases. Although freeze-drying is widely used to obtain solid formulations of mRNA-LNPs, highly hydrosoluble cryoprotectants, such as sucrose are necessary. However, sucrose is not a suitable excipient for… Continue reading Stable and inhalable powder formulation of mRNA-LNPs using pH-modified spray-freeze drying