Wet granulation

Freeze Granulation – homogeneous wet granulation of powders

Freeze Granulation is a wet granulation method where the powders, chemicals and binders are first mixed and dispersed in a solvent. In the next step the homogeneous slurry is pumped and sprayed through a nozzle to form droplets, which are sprayed into liquid nitrogen for instant freezing. In the final step the frozen granulate is moved to a freeze dryer where the solvent is sublimated leaving spherical, dust-free and homogeneous granules. The solvent could be water or organic solvents with a freezing point close to zero degree, like cyclohexane.

Please contact us for more information and a test-granulation of your powder system.

Diamond composite granules

Spherical, dust-free, homogeneous granules – no donuts!

LS-2 – Lab-scale Freeze Granulator

 

Granulation equipment

PowderPro supplies equipment for granulation of various powders and chemicals. Freeze Granulation for improved granule properties compared with spray drying. Granules with no void formation, no migration of fine particles or binders, and no formation of hard dry shell.

Spray cooling or rather called spray freezing is the first step in the freeze granulation process where a suspension is atomized, sprayed with a nozzle, into a chamber with liquid nitrogen. The small droplets are then rapidly frozen with a minimum of ice crystal growth. The frozen material (granules) are then transferred to a freeze dryer/lyophilizer where the ice is removed by sublimation, i e never go through a liquid state that ensure homogeneity preservation.

Please contact us for more information or if you have specific questions on your system and for a test-granulation of your powder system.

Suitable binder systems for Freeze Granulation

We have long experience in powder processing of different powder and chemical based systems. PVA-PEG binder system is one example of a commonly used system for water-based Freeze Granulation, please check our paper Development of water-based processing of silicon nitride materials.

Please use this form to contact us if you need support in suitable binder systems for your granulation.

Interested in test-granulation of your material?

If you would like to test-granulate your powders or chemicals using Freeze Granulation, please contact us for details. You send your material and binders to us, we make the test-granulation using freeze granulation and then send the granulated material (granulaes) back to you for your evaluation and testing.

Freeze granulation is considered to be a natural tool in most kind of material processing and development where optimal material performance is to be reached. PowderPro provides test granulations to reduced cost to evaluate the performance regarding your specific material system and application.

When purchasing of granulation equipment, PowderPro provides help in concepts for suspension formulation/preparation and how to operate the equipment to achieve high yield and high-quality granules.

 

LS-2 - Lab-scale Freeze Granulator